Gold Nanoparticles Biosynthesized from Synephrine Extracted from Citrus aurantium Peels and its Cytotoxicity Assay

Abstract

Nanotechnology is one of the most productive fields of study in current science.Nanoparticles (NPs) and nanomaterials are finding new uses at a rapid rate. The aim of the study that synthesis of nanoparticles from peels, which are considered Citrus auriantum. In this study synephrine was extracted from C. auriantum peels and biosynthesized gold nanoparticles from it, then characterization of synthesized gold nanoparticles (AuNps) by UV-visible spectroscopy Fourier Transform Infrared (FTIR) and FESEM which confirm the presence of AuNps in diameter size range to (20.8-34.3) nm and determined their toxicity assay on lymphoid human cell in 24 ,48 and 72 hours least cytotoxicity value was in 3.013 in 10 mg/ml for Citrus auriantum extract in 24 hours. It was concluded that synephrine extracted has no toxic effect inhibition rate of this maximum 5.698 in AuNp biosynthesized in 20 mg/ml concentration in 72 hours.