Role of Epstein–Barr virus (EBV) in human females with breast cancer

Abstract

Background: Epstein Barr Virus (EBV) contamination has been involved in pathogenesis of numerous forms of carcinomas, which includes gastric most carcinoma nasopharyngeal carcinoma, and bladder most carcinoma. It has been recently linked with cancer of the breast. The aim of this study is to estimating the relationship among Epstein Barr virus encoded minor piece of RNA (EBER) with tumors of the breast. 40 patients with breast cancer had been regained from the Pathology laboratory of AL-Sadder Medical City in Najaf AL-Ashraf Governorate/Iraq. Scientific records were investigated of the medical information and formalin permanent, paraffin implanted tumor tissue have been observed via Chromogenic in situ hybridization (CISH) method to the discovery of the protein of virus  EBER. The manifestation of EBER in most breast tissue in this study became 50% (11 from 22), in which tough association became observed amongst the communication from EBER and sufferers with cancer of the breast. Even as not create considerable variances between ISH terms of EBER with kind of cancer, age, lymph node metastasis and grade. Depedned on the outcomes of the present study, Epstein Barr virus  performs a prime part in the pathogenesis of most breast cancers.