The Effect of Heptachlor on Histology of Seminiferous Tubule and Mice Testis Activity

  • Nibal Kh. Mousa1, Labeeb A. Khadim1, Sarab S. kadhum1, Alaa Dh. Kadhum1, Sha Abrar N. Mohammad1, Mohammad Ab. Ayyash1


The study was aimed to illustrate the effect of heptachlor on seminiferous tubule and spermatic cells  in the testis of mice .Heptachlor  10 mg / kg  was given daily by gulping for five weeks. Mice were sacrificed after injected with colchicines in traperitonially , testis were collected after 7,21,36 days to study the effect of heptachlor on histo-testis and improved  heptachlor activity not as chemical mutagen but as a tumor promoter by act directly on DNA which reflected on decreasing testicular Leydig cell and spermatogenic deficiencies when comparison  with control and vitamin C.