Cytotoxic Effect of Hot Crude Extract of Fresh aloevera Plant on HepG2 Tumor Cell Line

Abstract

This work Aimed to study cytotoxic study crude extract of fresh leaves aloe vera plant on HepG2 tumor cell line. To achieve this goal, hot crude extract of fresh leaves Aloe vera plant, the study utilized on in vitro evaluated of cytotoxic effect of hot crude  extract on HepG2 tumor cell line at different concentrations and exposure at 72 hour treatment. The hot crude extract concentration ranging (0.3906-50) mg/ml in two fold serial dilution were used to treat HepG2 tumor cell line for 72 hour intervals. The results, appeared tumor cell line showed highest deity toward sensitivity toward the cytotoxic effect of the hot crude extra at concentration 3.125 mg/dl compare with normal cell line showed novel behavior effect, the lowest concentration of treatment give the most significant (P<0.01) inhibitor effect, however, lower inhibitor effect when exposure of 0.3906 mg/dl of hot crude extract.  The conclusion is that there is enough evidence to support the claim that Aloevera plant, is chemotherapeutic