Risk Factors Associated with Coronary Artery Disease in Iraqi Patients with Non-Alcoholic Fatty Liver

Abstract

The prevalence of Non-alcoholic fatty liver disease (NAFLD) is increasing every day. In addition to hepatic morbidity and mortality, also it is linked with an increased cardiovascular risk. NAFLD and Coronary artery disease (CAD) have a number of common risk factors. This study aimed to evaluate glycemic parameter, liver enzymes and lipid profile serum levels and its abilities to indicate the prognosis of CAD in patients with NAFLD. Serum from 180 Individuals were collected from both genders, and divided into three groups, blood samples were collected from participants and sent for biochemical tests in the laboratory. Data from the current study showed a significant increase in glycemic parameter and aspartate aminotransferase (AST). Also, the lipids profile included Total Cholesterol (TC), Triglyceride (TG), Low-density lipoproteins (LDL), Very Low-density lipoproteins (VLDL), shows a significant increase in serum level with the exception of High-density lipoproteins (HDL) in CAD group compared to NALD and control groups. Obesity and metabolic syndrome patients that suffers from NAFLD along with CAD have a higher serum level of fasting blood glucose (FBS), (TC, TG, LDL, VLDL) and AST when compared to NAFLD patients and healthy individuals, Therefore obesity and metabolic syndrome is considered a risk factor for CAD.