The Utility and Correlation of Tumor Marker CA125 with Breast Cancer in Iraqi Patients

Abstract

The current research aimed to detect the correlation between Cancer Antigen 125 (CA125) and breast cancer as well as study the impact of the metastasis of breast cancer on the level of CA125 in patients. Blood samples were collected from sixty patients with breast cancer and forty volunteers' heaths as control from many hospitals in Baghdad/Iraq between the periods (October 2021 to August 2022). The volunteer's blood samples were collected and tested with Cancer antigen 15-3 (CA 15-3) to confirm the absence of breast cancer. The blood samples were collected from these patients, and the healthy control samples were separated by centrifuge to get the serum and the concentration was measured using the electrochemiluminescence immunoassay (ELC) technique. The result showed an increase in the level of CA-125 among the patient's group in comparison with a healthy control group, and it was also shown an increasing level of CA125 when compared between the metastatic and non-metastatic breast cancer, with a highly significant increase between them (p< 0.001).