The Relationship between Some Biochemical Parameters and Type 2 Diabetes Mellitus among Iraqi Patients

Abstract

Type 2 diabetes (T2D) is a metabolic disorder that develops as different cell groups become resistant to insulin action on peripheral tissues. Eventually, the pancreas is unable to produce sufficient insulin to overcome this resistance resulting in insulin deficiency. This study included 120 blood samples divided into two groups, sixty from patients with T2DM recruited from the private clinic and sixty from normal healthy controls. All subjects underwent full history taking; thorough clinical examination; routine laboratory investigations including fasting blood sugar, hemoglobinA1c, total cholesterol, triglycerides, high-density lipoprotein-cholesterol, and low-density lipoprotein-cholesterol. The levels of serum glucose, total cholesterol, triglycerides, very low density lipoprotein and low density lipoprotein, showed significant increase in type II diabetes mellitus patients as compared to control group whereas the levels of high density lipoprotein showed no significant in patients with type II diabetes mellitus   comparison to control subjects ( P >0.01 ).