Grinding Halt Celiac Disease by Gluten Free Diet
The aim of this study is to assess the presence of autoantibodies in the studied groups and their significance in the detection of celiac disease (CD), and its relationship with gluten free diet (GFD). This study included 90 subjects who were divided into 60 CD and 30 control groups based on the age and gender. Also, the patients group further into three groups according to period of GFD : (13) without GFD patient , (30) with GFD for period ˂1year and (17) with GFD for period ˃1year . All serological tests of autoantibodies were conducted by the Enzyme linked Immunosorbent Assay (ELISA) technology. The findings revealed that all patients were seropositive for autoantibodies profile when compared to healthy controls, with a highly significant difference (p = 0.000). Relative remission of serological tests was seen in (30) patients treated for ˂1 year, while (17) patients treated for ˃1 year showed a clear reduction in autoantibodies levels when compared to (13) patients without GFD. In conclusion, immunological tests play an important role in the prognosis of CD. Repeating the immunologic screen 1 year after diagnosis and starting a GFD supports the routine measurement of using it as a gold standard test to confirm recovery of Iraqi CD patients.