Effect of Chitosan on Biofilm Formation of Multi-Drug Resistant Pseudomonas aeruginosa and Staphylococcus aureus

Abstract

This investigation examined chitosan's impact on clinically isolated bacteria's ability to form biofilms. Serial tests were used to create chitosan. At Medical City Hospital, 137 clinical burn swap samples were obtained from patients. Pseudomonas aeruginosa: was found in 69 of them, and Staphylococcus  aureus in 19, according to the Vitek 2 test. When cultured in microtiter plates, only 25 of P. aeruginosa and 5 of S. aureus were capable of forming biofilm. The outcomes demonstrated that at a concentration of 1.4 mg/ml, chitosan was more effective at preventing the production of biofilm. These findings suggest that in the future, this medication may also be utilized to treat MDR bacteria