Molecular detection of Fibronectin-binding Protein genes in Staphylococcus hominis Isolated from Blood Samples

Abstract

Coagulase-negative staphylococci (CoNS) are now recognized as a major cause of nosocomial infections in blood samples especially the species Staphylococcus hominis. S. hominis is often detected as a one of the pathogenic bacteria implicated for catheter-related blood stream infections and infective endocarditis. The aim of the study to isolation and identification of S. Hominis.  The blood samples (150) was collected  that this species was identified. The results of antibiotic resistance pattern showed a complete resistance (100 %) to pencilline and High resistance to Oxacillin (97.1 %) and Erythromycin (88.5 %). Also, high sensitivity was recorded for Teicoplanin, Vancomycin, and Linezolid. Molecular screening of fibronectin binding protein genes using PCR technique.  It was concluded that fnbA gene was detected in all isolates (100%), while fnbB gene was present in 17.14 % of the isolates.